Dr. Grace Holloway is a fictional character played by Daphne Ashbrook in the 1996 television film Doctor Who, a continuation of the long-running British science fiction television series Doctor Who. A cardiologist from San Francisco in 1999, she assists the Eighth Doctor in defeating the renegade Time Lord, the Master.

Daphne Lee Ashbrook is an American actress best known for playing Grace Holloway in Doctor Who: The Movie, Melora Pazlar in Star Trek: Deep Space Nine, Jackie Kowalski in Hollywood Heights, and Dawn Atwood in The OC.