Grace, Lady Mildmay was an English noblewoman, memoirist and medical practitioner. Her autobiography is one of the earliest existing autobiographies of an English woman. Originally from Wiltshire, she married Sir Anthony Mildmay in 1567 and moved to Apethorpe Palace, his father's home in Northamptonshire. She practised medicine on her family and others, with an extensive knowledge of medical theory, and a large repertoire of cures. Her writings included memoirs, medical papers and devotional meditations.

Sir Walter Mildmay was a statesman who served as Chancellor of the Exchequer to Queen Elizabeth I, and founded Emmanuel College, Cambridge.