Grand Isle County is a county in the U.S. state of Vermont. As of the 2020 census, the population was 7,293, making it Vermont's second-least populous county. Its shire town is North Hero. The county was created in 1802 and organized in 1805.

The Rutland Railroad was a railroad in the northeastern United States, located primarily in the state of Vermont but extending into the state of New York at both its northernmost and southernmost ends. After its closure in 1961, parts of the railroad were taken over by the State of Vermont in early 1963 and are now operated by the Vermont Railway.