The Grand Street Campus is a building used as the home for three high schools in Williamsburg, Brooklyn, New York City. The current building at 850 Grand Street opened in 1981; its identity as the Grand Street Campus dates to 1996. It is currently the home of The High School for Enterprise, Business and Technology, PROGRESS High School for Professional Careers, and the East Williamsburg Scholars Academy.

Williamsburg is a neighborhood in the New York City borough of Brooklyn, bordered by Greenpoint to the north; Bedford–Stuyvesant to the south; Bushwick and East Williamsburg to the east; and the East River to the west. It was an independent city until 1855, when it was annexed by Brooklyn; around that time, the spelling was changed from Williamsburgh to Williamsburg.