Great Bend is a borough in Susquehanna County, Pennsylvania, United States, 39 miles (63 km) north of Scranton. According to 2020 Census data, Great Bend's population was 634, down 13.6% from 2010. Great Bend sits along the Susquehanna River, less than two miles from the New York State border, and is located directly off Interstate 81. Several small manufacturers also call Great Bend home. Great Bend is considered a bedroom community of the Binghamton, NY metropolitan area. Downtown Binghamton is roughly 11 miles (18 km) from Great Bend. The borough has three public parks. Billy Greenwood Memorial Park on Kilrow Avenue and Veterans' Memorial Park on Spring St. overlook the Susquehanna River. Great Bend is within the Blue Ridge School District.

Susquehanna County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 38,434 Its county seat is Montrose. The county was created on February 21, 1810, from part of Luzerne County and later organized in 1812. It is named for the Susquehanna River. The county is part of the Northeast Pennsylvania region of the state.