The Great East Road is a major road in Zambia and the main route linking its Eastern Province with the rest of the country. It is also the major link between Zambia and Malawi and between Zambia and northern Mozambique. However, the route does not carry as much traffic as many of the other regional arterial roads and between the main cities it serves, Lusaka and Chipata, it passes through rural and wilderness areas. In Lusaka the road forms the main arterial road for the eastern suburbs. The entire route from Lusaka to Chipata and the border with Malawi is designated the T4 road on Zambia's road network.

In Zambia some roads are designated as numbered routes to help with navigation. There is a nationwide numbering scheme consisting of Inter-Territorial roads, Territorial roads, District roads and Rural roads.