The Great Indian Peninsula Railway was a predecessor of the Central Railway, whose headquarters was at the Boree Bunder in Mumbai. The Great Indian Peninsula Railway Company was incorporated on 1 August 1849 by the Great Indian Peninsula Railway Company Act 1849 of the Parliament of the United Kingdom. It had a share capital of 50,000 pounds. On 21 August 1847 it entered into a formal contract with the East India Company for the construction and operation of a railway line, 56 km long, to form part of a trunk line connecting Bombay with Khandesh and Berar and generally with the other presidencies of India. The Court of Directors of the East India Company appointed James John Berkeley as Chief Resident Engineer and Charles Buchanan Ker and Robert Wilfred Graham as his assistants. It was India's first passenger railway, the original 21 miles section opening in 1853, between Bombay (Mumbai) and Tanna. On 1 July 1925, its management was taken over by the Government. On 5 November 1951, it was incorporated into the Central Railway.

Central Railway is one of the 19 zones of Indian Railways. Its headquarters is in Mumbai at Chhatrapati Shivaji Maharaj Terminus. It has the distinction of operating the first passenger railway line in India, which opened from Mumbai to Thane on 16 April 1853.