The Great Siege of Montevideo, named as Sitio Grande in Uruguayan historiography, was the siege suffered by the city of Montevideo between 1843 and 1851 during the Uruguayan Civil War.

The Platine War was fought between the Argentine Confederation and an alliance consisting of the Empire of Brazil, Uruguay, and the Argentine provinces of Entre Ríos and Corrientes, with the participation of the Republic of Paraguay as Brazil's co-belligerent and ally. The war was part of a decades-long dispute between Argentina and Brazil for influence over Uruguay and Paraguay, and hegemony over the Platine region. The conflict took place in Uruguay and northeastern Argentina, and on the Río de la Plata. Uruguay's internal troubles, including the longrunning Uruguayan Civil War, were heavily influential factors leading to the Platine War.