The Great White Brotherhood, in belief systems akin to Theosophy and New Age, are said to be perfected beings of great power who spread spiritual teachings through selected humans. The members of the Brotherhood may be known as the Masters of the Ancient Wisdom, the Ascended Masters, the Church Invisible, or simply as the Hierarchy. The first person to talk about them in the West was Helena Petrovna Blavatsky (Theosophy), after she and other people claimed to have received messages from them. These included Helena Roerich, Alice A. Bailey, Guy Ballard, Geraldine Innocente, Elizabeth Clare Prophet, Bob Sanders, and Benjamin Creme.

Ascended masters in a number of movements in the theosophical tradition are held to be spiritually enlightened beings who in past incarnations were ordinary humans, but who have undergone a series of spiritual transformations originally called initiations.