Greece participated in the Eurovision Song Contest 2021 in Rotterdam, Netherlands. Greek-Dutch singer Stefania was internally selected by the Hellenic Broadcasting Corporation (ERT) to represent the nation with the song "Last Dance", written by Dimitris Kontopoulos, Arcade, and Sharon Vaughn. Stefania was due to compete in the 2020 contest with "Supergirl" before that event's eventual cancellation.
A green screen was used for the performance of "Last Dance" on stage.
Albania participated in the Eurovision Song Contest 2021 in Rotterdam, the Netherlands, with the song "Karma" performed by Anxhela Peristeri. Its entry was selected through the national selection competition Festivali i Këngës organised by Radio Televizioni Shqiptar (RTSH) in December 2020. To this point, the nation had participated in the Eurovision Song Contest sixteen times since its first entry in 2004. Prior to the contest, the song was promoted by a music video and various television and radio appearances in Albania, Greece, Kosovo and San Marino.
A video postcard introduced Anxhela Peristeri's shows, portraying a small house on the Hoge Brug in Maastricht decorated with personal pictures, a violin and other objects linked to the artist. At the end of the postcard, Peristeri greets the audience while playing a violin solo.