Greek Crimea concerns the ancient Greek settlements on the Crimean Peninsula. Greek city-states first established colonies along the Black Sea coast of Crimea in the 7th or 6th century BC. Several colonies were established in the vicinity of the Kerch Strait, then known as the Cimmerian Bosporus. The density of colonies around the Cimmerian Bosporus was unusual for Greek colonization and reflected the importance of the area. The majority of these colonies were established by Ionians from the city of Miletus in Asia Minor. By the mid-1st century BC the Bosporan Kingdom became a client state of the late Roman Republic, ushering in the era of Roman Crimea during the Roman Empire.

The recorded history of the Crimean Peninsula, historically known as Tauris, Taurica, and the Tauric Chersonese, begins around the 5th century BCE when several Greek colonies were established along its coast, the most important of which was Chersonesos near modern day Sevastopol, with Scythians and Tauri in the hinterland to the north. The southern coast gradually consolidated into the Bosporan Kingdom which was annexed by Pontus and then became a client kingdom of Rome. The south coast remained Greek in culture for almost two thousand years including under Roman successor states, the Byzantine Empire (341–1204), the Empire of Trebizond (1204–1461), and the independent Principality of Theodoro. In the 13th century, some Crimean port cities were controlled by the Venetians and by the Genovese, but the interior was much less stable, enduring a long series of conquests and invasions. In the medieval period, it was partially conquered by Kievan Rus' whose prince Vladimir the Great was baptised at Sevastopol, which marked the beginning of the Christianization of Kievan Rus'. During the Mongol invasion of Europe, the north and centre of Crimea fell to the Mongol Golden Horde, and in the 1440s the Crimean Khanate formed out of the collapse of the horde but quite rapidly itself became subject to the Ottoman Empire, which also conquered the coastal areas which had kept independent of the Khanate. A major source of prosperity in these times was frequent raids into Russia for slaves.