The Greek Orthodox Patriarchate of Alexandria and all Africa, also known as the Greek Orthodox Church of Alexandria, is an autocephalous patriarchate that is part of the Eastern Orthodox Church. Its seat is in Alexandria and it has canonical responsibility for the entire African continent.

The Eastern Orthodox Church, officially the Orthodox Catholic Church, and also called the Greek Orthodox Church or simply the Orthodox Church, is the second-largest Christian church, with approximately 230 million baptised members. It operates as a communion of autocephalous churches, each governed by its bishops via local synods. The church has no central doctrinal or governmental authority analogous to the head of the Catholic Church. Nevertheless, the Ecumenical Patriarch of Constantinople is recognised by them as primus inter pares, a title formerly given to the patriarch of Rome. As one of the oldest surviving religious institutions in the world, the Eastern Orthodox Church has played an especially prominent role in the history and culture of Eastern and Southeastern Europe.