The Greek Orthodox Patriarchate of Jerusalem, also known as the Greek Orthodox Church of Jerusalem, is an autocephalous church within the wider communion of Eastern Orthodox Christianity. Established in the mid-fifth century as one of the oldest patriarchates in Christendom, it is headquartered in the Church of the Holy Sepulchre in Jerusalem and led by the patriarch of Jerusalem, currently Theophilos III. The patriarchate's ecclesiastical jurisdiction includes roughly 200,000 to 500,000 Orthodox Christians across the Holy Land in Palestine, Jordan and Israel.

The Eastern Orthodox Church, officially the Orthodox Catholic Church, and also called the Greek Orthodox Church or simply the Orthodox Church, is the second-largest Christian church, with approximately 230 million baptised members. It operates as a communion of autocephalous churches, each governed by its bishops via local synods. The church has no central doctrinal or governmental authority analogous to the head of the Catholic Church. Nevertheless, the Ecumenical Patriarch of Constantinople is recognised by them as primus inter pares, a title formerly given to the patriarch of Rome. As one of the oldest surviving religious institutions in the world, the Eastern Orthodox Church has played an especially prominent role in the history and culture of Eastern and Southeastern Europe.