The Gregory Highway is a state highway in Queensland, Australia that serves the major coal-mining centres of Central Queensland. The highway was named after Augustus Gregory, an early explorer.

Central Queensland is an imprecisely-defined geographical division of Queensland that centres on the eastern coast, around the Tropic of Capricorn. Its major regional centre is Rockhampton. The region extends from the Capricorn Coast west to the Central Highlands at Emerald, north to the Mackay Regional Council southern boundary, and south to Gladstone. The region is also known as Capricornia. It is one of Australia's main coal exporting regions.