In London, the Greyfriars was a Conventual Franciscan friary that existed from 1225 to 1538 on a site at the North-West of the City of London by Newgate in the parish of St Nicholas in the Shambles. It was the second Franciscan religious house to be founded in the country. The establishment included a conventual church that was one of the largest in London; a studium or regional university; and an extensive library of logical and theological texts. It was an important intellectual centre in the early fourteenth century, rivalled only by Oxford University in status. Members of the community at that time included William of Ockham, Walter Chatton and Adam Wodeham. It flourished in the fourteenth and fifteenth century but was dissolved in 1538 at the instigation of Henry VIII as part of the Dissolution of the Monasteries. Christ's Hospital was founded in the old conventual buildings, and the church was rebuilt completely by Sir Christopher Wren as Christ Church Greyfriars after the original church was almost completely destroyed in the Great Fire of London of 1666. The building now standing on the site, designed by Arup Group Limited, is currently occupied by Merrill Lynch.

William of Ockham or Occam was an English Franciscan friar, scholastic philosopher, apologist, and Catholic theologian, who is believed to have been born in Ockham, a small village in Surrey. He is considered to be one of the major figures of medieval thought and was at the centre of the major intellectual and political controversies of the 14th century. He is commonly known for Occam's razor, the methodological principle that bears his name, and also produced significant works on logic, physics and theology. William is remembered in the Church of England with a commemoration on the 10th of April.