Griffin v. County School Board of Prince Edward County, 377 U.S. 218 (1964), is a case decided by the Supreme Court of the United States that held that the County School Board of Prince Edward County, Virginia's decision to close all local, public schools and provide vouchers to attend private schools were constitutionally impermissible as violations of the Equal Protection Clause of the Fourteenth Amendment.

Prince Edward County is located in the Commonwealth of Virginia. As of the 2020 census, the population was 21,849. Its county seat is Farmville.