The Guatemalan Highlands is an upland region in southern Guatemala, lying between the Sierra Madre de Chiapas to the south and the Petén lowlands to the north.

The Sierra Madre is a major mountain range in Central America. It is known as the Sierra Madre de Chiapas in Mexico. It crosses El Salvador, Guatemala, Mexico and Honduras. The Sierra Madre is part of the American Cordillera, a chain of mountain ranges that consists of an almost continuous sequence of mountain ranges that form the western "backbone" of North America, Central America, and South America.