Guillaume Latendresse is a Canadian former professional ice hockey player. He was drafted by the Montreal Canadiens of the National Hockey League (NHL) in the second round, 45th overall, of the 2005 NHL Entry Draft, and played in the NHL with Montreal, the Minnesota Wild and the Ottawa Senators. Latendresse was born in LaSalle, Quebec, but grew up in Sainte-Catherine, Quebec.

The 2005 NHL Entry Draft was the 43rd NHL Entry Draft. Originally scheduled to be held on June 25, the 2004–05 NHL lockout led to the draft being postponed to July 30.