Gula was a Mesopotamian goddess of medicine, portrayed as a divine physician and midwife. Over the course of the second and first millennia BCE, she became one of the main deities of the Mesopotamian pantheon, and eventually started to be viewed as the second highest ranked goddess after Ishtar. She was associated with dogs, and could be depicted alongside these animals, for example on kudurru, and receive figurines representing them as votive offerings.

Ninisina was a Mesopotamian goddess who served as the tutelary deity of the city of Isin. She was considered a healing deity. She was believed to be skilled in the medical arts, and could be described as a divine physician or midwife. As an extension of her medical role, she was also believed to be capable of expelling various demons. Her symbols included dogs, commonly associated with healing goddesses in Mesopotamia, as well as tools and garments associated with practitioners of medicine.