Gulfport–Biloxi International Airport is a joint civil–military public-use airport three nautical miles (6 km) northeast of the central business district of Gulfport, a city in Harrison County, Mississippi, United States. It is owned by the Gulfport–Biloxi Regional Airport Authority and serves the Gulf Coast area.

Gulfport is the second-most populous city in the U.S. state of Mississippi after the state capital, Jackson. Along with Biloxi, Gulfport is the co-county seat of Harrison County and part of the Gulfport–Biloxi metropolitan area. As of the 2020 census, Gulfport has a population of 72,926; the metro area has a population of 416,259. Gulfport lies along the gulf coast of the United States in southern Mississippi, taking its name from its port on the Gulf Coast on the Mississippi Sound. It is home to the U.S. Navy Atlantic Fleet Seabees.