Saint Gontrand called Gontran, Guntram, Gunthram and Guntramnus, was the king of the Kingdom of Orleans from AD 561 to AD 592. He was second eldest surviving son of Chlothar I and Ingunda. On his father's death in 561, he became king of a fourth of the Kingdom of the Franks, made his capital at Orléans; the name "Gontrand" denotes " War Raven". King Gontrand had something of that fraternal love, he married Marcatrude, daughter of Magnar, sent his son Gundobad to Orléans. But after she had a son Marcatrude was jealous, proceeded to bring about Gundobad's death, she sent poison, they say, poisoned his drink. And upon his death, by God's judgment she lost the son she had and incurred the hate of the king, was dismissed by him, died not long after. After her he took Austerchild named Bobilla, he had by her two sons, of whom the older was called the younger Chlodomer. Gontrand had a period of intemperance, he was overcome with remorse for the sins of his past life, spent his remaining years repenting of them, both for himself and for his nation.

In atonement, he fasted, prayed and offered himself to God. Throughout the balance of his prosperous reign he attempted to govern by Christian principles. According to St. Gregory of Tours, he was the protector of the oppressed, caregiver to the sick, the tender parent to his subjects, he was generous with his wealth in times of plague and famine. He and justly enforced the law without respect to person, yet was ready to forgive offences against himself, including two attempted assassinations. Gontrand monasteries. St. Gregory related that the king performed many miracles both before and after his death, some of which St. Gregory claimed to have witnessed himself. In 567, his elder brother Charibert I died and his lands of the Kingdom of Paris were divided between the surviving brothers: Gontrand, Sigebert I, Chilperic I, they shared his realm. Charibert's widow, proposed a marriage with Gontrand, the eldest remaining brother, though a council convened at Paris as late as 557 had forbidden such tradition as incestuous.

Gontrand decided to house her more safely, though unwillingly, in a monastery in Arles. In 573, Gontrand was caught in a civil war with his brother Sigebert I of Austrasia, in 575 summoned the aid of their brother Chilperic I of Soissons, he reversed his allegiance due to the character of Chilperic, if we may give him the benefit of the doubt in light of St. Gregory's commendation, Chilperic retreated, he thereafter remained an ally of Sigebert, his wife, his sons until his death. When Sigebert was assassinated in 575, Chilperic invaded the kingdom, but Gontrand sent his general Mummolus, always Gontrand's greatest weapon, for he was the greatest general in Gaul at the time, to remove him. Mummolus defeated Chilperic's general Desiderius and the Neustrian's forces retreated from Austrasia. In 577, Chlothar and Clodomir, his two surviving children, died of dysentery and he adopted as his son and heir Childebert II, his nephew, Sigebert's son, whose kingdom he had saved two years prior. However, Childebert did not always prove faithful to his uncle.

In 581, Chilperic took many of Gontrand's cities and in 583, he allied with Childebert and attacked Gontrand. This time Gontrand made peace with Childebert retreated. In 584, he returned Childebert's infidelity by invading his land and capturing Tours and Poitiers, but he had to leave to attend the Baptism of Chlothar II, his other nephew, who now ruled in Neustria. Supposed to take place on 4 July, the feast of St. Martin of Tours, in Orléans, it did not and Gontrand turned to invade Septimania. Peace was soon made. In 584 or 585, one Gundowald claimed to be an illegitimate son of Chlothar I and proclaimed himself king, taking some major cities in southern Gaul, including Poitiers and Toulouse, which belonged to Gontrand. Gontrand marched against him. Gundowald fled to Comminges and Gontrand's army proceeded to besiege the citadel, he could not capture it, but did not need to: Gundowald's followers gave him over and he was executed. In 587, Fredegund failed, he went, on 28 November. This was called the Treaty of Andelot and it endured until Gontrand died.

In 587, Gontrand compelled obedience from Waroch II, the Breton ruler of the Vannetais. He forced the renewal of the oath of 578 in writing and demanded 1,000 solidi in compensation for raiding the Nantais. In 588, the compensation was not yet paid, as Waroch promised it to both Gontrand and Chlothar II, who had suzerainty over Vannes. In 589 or 590, Gontrand sent an expedition against Waroch under Beppolem and Ebrachain, mutual enemies. Ebrachain was enemy of Fredegund, who sent the Saxons of Bayeux to aid Waroch. Beppolem fought alone for three days before dying, at which point Waroch tried to flee to the Channel Islands, but Ebracha

Center for International Blood and Marrow Transplant Research

The Center for International Blood & Marrow Transplant Research, or CIBMTR, is a research facility that focuses on hematopoietic cell transplantation and cellular therapy research. The center operates a combined research program of the National Marrow Donor Program and the Medical College of Wisconsin. On July 1, 2004, in pursuit of a mission to improve transplantation access and outcomes for patients, the CIBMTR was established; the new organization joined together the research programs of the National Marrow Donor Program and the International Bone Marrow Transplant Registry at the Medical College of Wisconsin. In 1972, just four years after the first successful hematopoietic cell transplantation, pioneers in the field of HCT realized the significance of what they were undertaking. Several of the pioneers in this evolving science understood the importance of collaborating to better understand the data being generated at individual centers. Dr. Mortimer M. Bortin and several colleagues established the IBMTR at the Medical College of Wisconsin to do just that.

Physicians in the field agreed to voluntarily contribute their patient data to this outcomes registry. At the time, there were only about 12 transplant centers and fewer than 50 patients per year worldwide receiving a transplant. In 1986, the U. S. Navy established the National Bone Marrow Donor Registry with one full-time employee housed at the St. Paul, MN, American Red Cross and a sub-contract with the University of Minnesota for computer support and data management; the first donor search was processed in September 1987, the first National Marrow Donor Program -facilitated transplant took place in December 1987. Again, the founders knew the critical nature of collecting outcomes data and conducting collaborative research to improve outcomes, requiring from that first unrelated transplant that transplant centers report their patient outcomes to the NMDP. Observational research is a core activity of CIBMTR. Investigators are invited to propose studies; these research studies culminate in publications in peer-reviewed journals and move the field of hematopoietic cell transplantation toward improved outcomes and higher quality of life.

Since its inception in 1972, CIBMTR data and statistical support have resulted in more than 700 peer-reviewed publications addressing HCT. Studies are conducted within a Working Committee structure, they are guided by Co-Chairs who are experts in the relevant field, by Scientific Directors who are experienced transplant physicians with MS degrees in biostatistics or related fields. MS biostatisticians coordinate Working Committee activities and participate in individual studies, with oversight provided by PhD biotatisticians. Investigators from around the world are participating in more than 250 CIBMTR studies. Collected data can be accessed for patient care decisions, developing research studies, transplant center administrative needs, CIBMTR research; every year, a variety of resources are developed from CIBMTR data, including publications, slide sets, Web resources, more. Investigators, physicians and others interested in hematopoeitic cell transplantation outcomes can access these resources below.

They collect outcomes data on every allogeneic transplantation performed in the U. S.. U. S. transplant centers voluntarily submit autologous transplantation data, transplant centers worldwide voluntarily submit both autologous and allogeneic transplantation data. As a result, their clinical database now contains information on more than 330,000 transplant recipients. CIBMTR supports investigators in conducting HCT observational studies. Data available for this research includes: Baseline recipient data Diagnosis – disease sub-classification or histology, disease status at transplant, molecular markers, pre-HCT disease treatments Demographic – socioeconomic information, age, race/ethnicity Transplant procedure – HLA typing, conditioning regimen, graft source, mobilization regimen, graft manipulation Clinical – coexisting diseases and disorders, pre-HCT infections, HCT historyBaseline donor data Demographics HLA typing Infection disease markers Pre-donation CBC and differential Pre-donation toxicities Filgrastim administrationFollow-up recipient data Collected at 100 days, 6 months, annually after HCT: Information collected about all recipients Survival Subsequent HCT or cellular therapy Initial neutrophil and platelet recovery Graft vs. Host Disease - severity and treatment status New malignancy, lymphoproliferative, or myelopoliferative disease/disorder Chimerism studies Disease assessment at the time of best response to HCT Post-HCT therapy Relapse or progression post-HCT Disease status at time of most recent assessment Additional information collected about "research-track" recipients Growth factor and cytokine therapy Hematologic findings at time of most recent assessment Immune reconstitution Engraftment syndrome Graft vs. Host Disease - symptoms and treatment drugs Infection prophylaxis Infection Organ function/impairments Functional statusFollow-up donor data Collected at 2 days, 1 week and weekly until donor reports full recovery at 1 month, 6 months and annually after donation: Donor outcomes – post-donation CBC and differential, post-donation toxicities, adverse events Product analysis – cell counts, volume The NMDP Research Sample Repository contains blood samples from related and unrelated recipient/donor pairs, collected pre-HCT.

These samples can be used for local research studies as well as for CIBMTR research studies. According to the CIB

Roscoe, Texas

Roscoe is a city in Nolan County in the U. S. state of Texas near the intersection of Interstate 20 and US Highway 84. The Union Pacific Railroad passes through the center of the city. Another rail line, the Roscoe and Pacific Railway, used to extend 50 miles from Roscoe to Fluvanna, passing through Snyder, Texas. Built in 1908, the railway served as a bridge between the Atchison and Santa Fe Railway and the Texas and Pacific Railway. Although the RS&P became one of the most profitable short lines in the nation during its early years, passenger service was discontinued in 1953, freight service was discontinued in the late 1970s, the tracks were removed in 1984. Roscoe is located at 32°26′45″N 100°32′19″W. According to the United States Census Bureau, the city has a total area of 1.9 square miles, all of it land. The population was 1,378 at the 2000 census, but has since decreased to only 900. Need Citation, Disagrees with Side Bar - History According to the Köppen climate classification system, Roscoe has a semiarid climate, BSk on climate maps.

As of the census of 2000, 1,380 people, 509 households, 382 families resided in the city. The population density is 728.1 people per square mile. The 588 housing units averaged 310.7/sq mi. The racial makeup of the city were 75.18% White, 1.09% African American, 0.44% Native American, 0.15% Asian, 20.17% from other races, 2.98% from two or more races. Hispanics or Latinos of any race were 36.94% of the population. Of 509 households, 32.6% had children under the age of 18 living with them, 61.5% were married couples living together, 10.2% had a female householder with no husband present, 24.8% were not families. About 22.8% of all households were made up of individuals and 13.0% had someone living alone, 65 years of age or older. The average household size was 2.63 and the average family size was 3.09. In the town, the population was distributed as 28.2% under the age of 18, 6.9% from 18 to 24, 23.3% from 25 to 44, 22.3% from 45 to 64, 19.3% who were 65 years of age or older. The median age was 38 years.

For every 100 females, there were 89.8 males. For every 100 females age 18 and over, there were 90.6 males. The median income for a household in the city is $23,816, for a family was $28,393. Males had a median income of $25,313 versus $20,000 for females; the per capita income for the city was $11,792. About 20.6% of families and 25.2% of the population were below the poverty line, including 34.9% of those under age 18 and 17.1% of those age 65 or over. The Roscoe Wind Farm and operated by E. ON Climate and Renewables, is one of the world's largest capacity wind farms with 627 wind turbines and a total installed capacity of 781.5 MW. At the time of its completion, it was the largest wind farm in the world, surpassing the nearby 735.5-MW Horse Hollow Wind Energy Center. In 2012, it was overtaken by California's 1,020-MW Alta Wind Energy Center; the project cost more than $1 billion and provides enough power for more than 250,000 average Texan homes. A landowner can earn between $500 and $1,000 per windmill per year.

The City of Roscoe is served by Roscoe Collegiate Independent School District. The recent wind development in the area has enabled Roscoe ISD to update its aging facilities built in the era of the Works Progress Administration. In the 2012 -- 13 school year, all of the district's students will be in updated buildings. Roscoe Collegiate ISD operates one of 50 Early College High Schools in Texas in partnership with Western Texas College in Snyder. Students of Roscoe Collegiate High School have the ability to earn an associate degree from Western Texas College at the time of high school graduation; the mascot of Roscoe Collegiate High School is the Plowboys. Roscoe is home to the Plowboy Mudbog, held twice a year, during the Independence Day Celebration, held on July 4 weekend, in October coinciding with the Wind Festival; the July mudbog draws around 70 to 80 trucks competing for prize and bragging rights. J. J. Pickle, U. S. congressman Double Mountain Fork Brazos River Hobbs, Texas Brazos Wind Farm Wind power in Texas U.

S. Route 84 City of Roscoe website Roscoe, TX from the Handbook of Texas Online U. S. Geological Survey Geographic Names Information System: Roscoe, TX Photos of West Texas and Llano Estacado