Henry Otto Wittpenn was an American politician who served as the Mayor of Jersey City, New Jersey, from January 1, 1908, to June 16, 1913. He was a member of the New Jersey State Highway Commission and was the president of both the Hoboken Land and Improvement Company and the First National Bank of Hoboken. He was also a director of the First National Bank of Jersey City.

The Mayor of the City of Jersey City is the head of the executive branch of the government of Jersey City, New Jersey, United States. The mayor has the duty to enforce the municipal charter and ordinances; prepare the annual budget; appoint deputy mayors, department heads, and aides; and approve or veto ordinances passed by the City Council. The mayor is popularly elected in a nonpartisan general election. The office is held for a four-year term without term limits, although the current term is a four-and-a-half-year term, due to a change in election dates.