HMG-CoA reductase
Videos
HMG-CoA reductase is the rate-limiting enzyme—NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34—of the mevalonate pathway, which is the metabolic pathway that produces cholesterol and other is
HMG-CoA reductase (NADPH), Human
1dq8: COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG AND COA
1dq9: COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA
1dqa: COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG, COA, AND NADP+
Mevalonate pathway
Videos
The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway, is an essential metabolic pathway present in eukaryotes, archaea, and some bacteria. The pathway produces two
HMG-CoA reductase
…yl-glutaryl-coenzyme A reductase; official symbol HMGCR) is the rate-limiting enzyme—NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34—of the mevalonate pathway, which is the metabolic pathway that produces cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonic acid, a necessary…
M3kwiki 3
M35bp K
Mdd 2
Mevalonate pathway diagram showing the conversion of acetyl-CoA into isopentenyl pyrophosphate, the essential building block of all isoprenoids. The eukaryotic variant is shown in black. Archaeal variants are shown in red and blue.