HMS Ambuscade was a British Royal Navy destroyer which served in the Second World War. She and her Thornycroft competitor, HMS Amazon, were prototypes designed to exploit advances in construction and machinery since World War I and formed the basis of Royal Navy destroyer evolution up to the Tribal of 1936.

HMS Amazon was a prototype design of destroyer ordered for the Royal Navy in 1924. She was designed and built by Thornycroft in response to an Admiralty request for a new design of destroyer incorporating the lessons and technological advances of the First World War. Their great rivals Yarrow produced a similar, competitive design — that of Ambuscade.