HMS Childers was a brig-sloop of the British Royal Navy, initially armed with 10 carriage guns which were later increased to 14 guns. The first brig-sloop to be built for the Navy, she was ordered from a commercial builder during the early years of the American War of Independence, and went on to support operations in the English Channel and the Caribbean. Laid up for a time after the end of the American War of Independence, she returned to service shortly before the outbreak of the French Revolutionary Wars. She had an active career in both the French Revolutionary and Napoleonic Wars, capturing numerous French privateers and during the Gunboat War participated in a noteworthy single-ship action. The navy withdrew her from service at the beginning of 1811, at which time she was broken up.

Admiral James O'Brien, 3rd Marquess of Thomond, GCH (1769–1855), styled Lord James O'Brien from 1809 to 1846, was a British naval officer and Chief of Clan O'Brien.