The seventh HMS Dreadnought was the United Kingdom's first nuclear-powered submarine, built by Vickers Armstrongs at Barrow-in-Furness. Launched by Queen Elizabeth II on Trafalgar Day 1960 and commissioned into service with the Royal Navy in April 1963, she continued in service until 1980. The submarine was powered by a S5W reactor, a design made available as a direct result of the 1958 US–UK Mutual Defence Agreement.

A nuclear submarine is a submarine powered by a nuclear reactor, but not necessarily nuclear-armed. Nuclear submarines have considerable performance advantages over "conventional" submarines. Nuclear propulsion, being completely independent of air, frees the submarine from the need to surface frequently, as is necessary for conventional submarines. The large amount of power generated by a nuclear reactor allows nuclear submarines to operate at high speed for long periods, and the long interval between refuelings grants a range virtually unlimited, making the only limits on voyage times being imposed by such factors as the need to restock food or other consumables.