HOTAIR is a human gene located between HOXC11 and HOXC12 on chromosome 12. It is the first example of an RNA expressed on one chromosome that has been found to influence the transcription of the HOXD
HOTAIR_1: Secondary structure taken from the Rfam database. Family RF01904
HOTAIR_2: Secondary structure taken from the Rfam database. Family RF01905
HOTAIR_3: Secondary structure taken from the Rfam database. Family RF01906
HOTAIR_4: Secondary structure taken from the Rfam database. Family RF01907
Polycomb-group proteins are a family of protein complexes first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place. Polycomb-group proteins are we
The Polycomb gene FIE is expressed (blue) in unfertilised egg cells of the moss Physcomitrella patens (right) and expression ceases after fertilisation in the developing diploid sporophyte (left). In situ GUS staining of two female sex organs (archegonia) of a transgenic plant expressing a translational fusion of FIE-uidA under control of the native FIE promoter