The Hadharem or the Hadhrami are an Arab sub-ethnic group indigenous to the Hadhramaut region in South Arabia, which is part of modern-day eastern Yemen. They speak Hadhrami Arabic. Among the two million inhabitants of Hadhramaut, there are about 1,300 distinct tribes.

Hadhramaut is a geographic region in South Arabia, comprising eastern Yemen, parts of western Oman and southern Saudi Arabia. The name is of ancient origin, and is retained in the name of the Yemeni Governorate of Hadhramaut. The people of Hadhramaut are called Hadarem. They formerly spoke Hadramautic, an old South Arabian language, but they now predominantly speak Hadhrami Arabic.