"Hail Mary" is a song by American rapper Tupac Shakur from his fifth studio album, The Don Killuminati: The 7 Day Theory (1996). It was released after his September 1996 murder under the Makaveli stage name as the album's third single. Hail Mary features rap verses by Kastro, Young Noble and Yaki Kadafi of the Outlawz rap group and vocals from reggae musician Prince Ital Joe. A music video was shot for the song and can be found on the DualDisc of The Don Killuminati: The 7 Day Theory.

Tupac Amaru Shakur, also known by his stage names 2Pac and Makaveli, was an American rapper and songwriter. Considered to be one of the most influential and successful rappers of all time, academics regard him as one of the most influential music artists of the 20th century and also a politically-conscious activist voice for Black America. Shakur is among the best-selling music artists, having sold more than 75 million records worldwide. His lyrical content has been noted for addressing social injustice, political issues and the marginalization of African-Americans, but also synonymous with violent rap lyrics.