Halle (Saale) Hauptbahnhof is the main railway station in the city of Halle (Saale) in southern part of the German state of Saxony-Anhalt. The station is situated east of the city centre and is a category 2 station.

Halle (Saale), or simply Halle (German: [ˈhalə]; from the 15th to the 17th century: Hall in Sachsen; until the beginning of the 20th century: Halle an der Saale ; from 1965 to 1995: Halle/Saale) is the largest city of the German state of Saxony-Anhalt, the fifth most populous city in the area of former East Germany after (East) Berlin, Leipzig, Dresden and Chemnitz as well as the 31st largest city of Germany, and with around 244,000 inhabitants, it is slightly more populous than the state capital of Magdeburg. Together with Leipzig, the largest city of Saxony, Halle forms the polycentric Leipzig-Halle conurbation. Between the two cities, in Schkeuditz, lies Leipzig/Halle International Airport. The Leipzig-Halle conurbation is at the heart of the larger Central German Metropolitan Region.