Hamburg-Harburg or Harburg is one of four operational main-line railway stations (Fernbahnhöfe) in the city of Hamburg, Germany. Opened on 1 May 1897, it is situated on the Hannover-Hamburg, Wanne-Eickel-Hamburg and Lower Elbe lines as well as the Harburg S-Bahn line. Train services are operated by Deutsche Bahn and Metronom with the rapid transit station being served by the Hamburg S-Bahn. The station is managed by DB Station&Service.

The Hanover–Hamburg railway is one of the most important railway lines in Lower Saxony and Germany. It links the Lower Saxon state capital of Hanover with Hamburg, running through Celle, Uelzen and Lüneburg.