The Hamiltons of the United States are a family of Scottish origin, whose most prominent member was Alexander Hamilton (1755/57–1804), one of the Founding Fathers of the United States. Their ancestors and relations in Scotland included the Lairds of Kerelaw Castle in Stevenston, North Ayrshire, of the Cambuskeith branch of Clan Hamilton.

The Clan Hamilton, or House of Hamilton, is a Scottish clan of the Scottish Lowlands.