Hancock County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 29,095. Its county seat is New Cumberland and its largest city is Weirton. The county was created from Brooke County in 1848 and named for John Hancock, first signer of the Declaration of Independence. Located at the tip of the state's Northern Panhandle, Hancock County is the northernmost point in both West Virginia and, by some definitions, the Southern United States. Hancock County is part of the Weirton-Steubenville, WV-OH Metropolitan Statistical Area, which is also included in the Pittsburgh-New Castle-Weirton, PA-WV-OH Combined Statistical Area.

New Cumberland is a city in and the county seat of Hancock County, West Virginia, United States, along the Ohio River. The population was 1,020 as of the 2020 census. It is part of the Weirton–Steubenville metropolitan area and is located near the Mountaineer Casino, Racetrack and Resort.