Hardeeville is a city in Jasper and Beaufort counties in the U.S. state of South Carolina. The population was 7,473 as of the 2020 census, an increase of over 150% since 2010. Hardeeville is included within the Hilton Head Island–Bluffton metropolitan area.

U.S. Route 17 or U.S. Highway 17 (US 17), also known as the Coastal Highway, is a north–south United States Numbered Highway that spans in the Southeastern United States. It runs close to the Atlantic Coast for much of its length, with the exception of the portion between Punta Gorda and Jacksonville, Florida, and the portion from Fredericksburg to Winchester, Virginia, both of which follow a more inland route. Major metropolitan areas served along US 17's route include the Punta Gorda, Greater Orlando, and Jacksonville metropolitan area, the Brunswick and Savannah metropolitan areas in Georgia, the Charleston and Myrtle Beach metropolitan areas in South Carolina, the Cape Fear and New Bern metropolitan areas in North Carolina, and the Hampton Roads and Winchester metropolitan areas in Virginia.