Harley Quinn is an American animated black comedy superhero television series based on the DC Comics character of the same name created by Paul Dini and Bruce Timm. The series is written and executive-produced by Justin Halpern, Patrick Schumacker, and Dean Lorey, and follows the adventures of Harley Quinn and her partner Poison Ivy after leaving her boyfriend, the Joker. The show premiered on November 29, 2019.

Harley Quinn is a character appearing in American comic books published by DC Comics. She was created by Paul Dini and Bruce Timm for Batman: The Animated Series as a henchwoman for the Joker, and debuted in its 22nd episode, "Joker's Favor", on September 11, 1992. While intended to appear in one episode, Quinn became a recurring character within the DC Animated Universe (DCAU) as the Joker's sidekick and love interest, and was adapted into DC Comics' canon seven years later, beginning with the one-shot Batman: Harley Quinn #1. Quinn's origin story features her as a former psychologist at Gotham City's Arkham Asylum who was manipulated by and fell in love with the Joker, her patient, eventually becoming his accomplice and lover. The character's alias is a play on the stock character Harlequin from the 16th-century Italian theater commedia dell'arte.