Harrisonburg is an independent city in the Shenandoah Valley region of the Commonwealth of Virginia in the United States. It is also the county seat of the surrounding Rockingham County, although the two are separate jurisdictions. At the 2020 census, the population was 51,814. The Bureau of Economic Analysis combines the city of Harrisonburg with Rockingham County for statistical purposes into the Harrisonburg, Virginia Metropolitan Statistical Area, which had an estimated population of 126,562 in 2011.

The Shenandoah Valley is a geographic valley and cultural region of western Virginia and the Eastern Panhandle of West Virginia in the United States. The Valley is bounded to the east by the Blue Ridge Mountains, to the west by the eastern front of the Ridge-and-Valley Appalachians, to the north by the Potomac River, to the south by the James River, and to the Southwest by the New River Valley. The cultural region covers a larger area that includes all of the Valley plus the Virginia Highlands to the west and the Roanoke Valley to the south. It is physiographically located within the Ridge and Valley Province and is a portion of the Great Appalachian Valley.