Harthill is a rural village split between North Lanarkshire and West Lothian in Scotland, with most of the village in North Lanarkshire. It is located about halfway between Glasgow, 21 miles to the west, and Edinburgh, 25 miles (40 km) to the east. It lies on the River Almond about 2+1⁄2 miles (4 km) west of the small town of Whitburn. The closest major towns are Bathgate, 6 miles (9.7 km) away, and Livingston, 10 miles (16 km) away. Major towns within North Lanarkshire, such as Wishaw, Airdrie, Motherwell, Coatbridge and Bellshill are all around 10 to 15 miles to the west. The M8 motorway bypasses the village and Harthill has a service station named after it.

The M8 is the busiest motorway in Scotland. It connects the country's two largest cities, Glasgow and Edinburgh, and serves other large communities including Airdrie, Coatbridge, Greenock, Livingston and Paisley. The motorway is 60 miles (97 km) long. A major construction project to build the final section between Newhouse and Baillieston was completed on 30 April 2017. The motorway has one service station, Heart of Scotland Services, previously named Harthill due to its proximity to the village.