Haute-Loire is a landlocked department in the Auvergne-Rhône-Alpes region of south-central France. Named after the Loire River, it is surrounded by the departments of Loire, Ardèche, Lozère, Cantal and Puy-de-Dôme. In 2019, it had a population of 227,570; its inhabitants are called Altiligériens in French.

Auvergne-Rhône-Alpes is a region in southeast-central France created by the 2014 territorial reform of French regions; it resulted from the merger of Auvergne and Rhône-Alpes. The new region came into effect on 1 January 2016, after the regional elections in December 2015.