Haute-Vienne is a département in the Nouvelle-Aquitaine region in southwest-central France. Named after the Vienne River, it is one of the twelve départements that together constitute Nouvelle-Aquitaine. The prefecture and largest city in the department is Limoges, the other towns in the department each having fewer than twenty thousand inhabitants. Haute-Vienne had a population of 372,359 in 2019.

Nouvelle-Aquitaine is the largest administrative region in France by area, spanning the west and southwest of Metropolitan France. The region was created in 2014 by the merging of Aquitaine, Limousin, and Poitou-Charentes in a territorial reform. Nouvelle-Aquitaine has an area of 84,035.7 km2 (32,446.4 sq mi) – more than 1⁄7 of Metropolitan France – and has a population of 6,033,952 as of 2020. The new region was established on 1 January 2016, following the regional elections in December 2015.