Haute Matsiatra is a region in Madagascar. It borders Amoron'i Mania region in north, Vatovavy-Fitovinany in east, Ihorombe in south and Atsimo-Andrefana in west. The capital of the region is Fianarantsoa, and the population was 1,447,296 in 2018. The area is 21,080 km2 (8,139 sq mi).

Amoron'i Mania is a region in central Madagascar bordering Vakinankaratra Region in north, Atsinanana in northeast, Fitovinany in southeast, Haute Matsiatra in south, Atsimo-Andrefana in southwest and Menabe in west.