Haydarpaşa is a locality within the Kadıköy and Üsküdar districts on the Asian part of Istanbul, Turkey. Haydarpaşa is named after Ottoman Vizier Haydar Pasha. The place, on the coast of Sea of Marmara, borders to Harem in the northwest and Kadıköy in the southeast. It is a historical area with almost solely public buildings. Haydarpaşa is administered by the Mukhtars of Rasımpaşa and Osmanağa parishes.

Haydarpaşa station is a railway station in Istanbul, that was, until 2012 the main city terminal for trains travelling to and from the Anatolian side of Turkey. It used to be Turkey's busiest railway station. The station building still houses the headquarters for District 1 of the State Railways but since a fire in 2010 the station has not been in use and its future remains uncertain.