The Hearst Memorial Mining Building at the University of California, Berkeley, is home to the university's Materials Science and Engineering Department, with research and teaching spaces for the subdisciplines of biomaterials; chemical and electrochemical materials; computational materials; electronic, magnetic, and optical materials; and structural materials. The Beaux-Arts-style Classical Revival building is listed in the National Register of Historic Places and is designated as part of California Historical Landmark #946. It was designed by John Galen Howard, with the assistance of architect and Berkeley alumna Julia Morgan and the Dean of the College of Mines at that time, Samuel B. Christy. It was the first building on that campus designed by Howard. Construction began in 1902 as part of the Phoebe Hearst campus development plan. The building was dedicated to the memory of her husband George Hearst, who had been a successful miner.

George Hearst was an American businessman, politician, and patriarch of the Hearst business dynasty. After growing up on a small farm in Missouri, he founded many mining operations, and is known for developing and expanding the Homestake Mine in the late 1870s in the Black Hills of South Dakota. In 1879, he listed it on the New York Stock Exchange and went on to other pursuits. The mine's gold production continued uninterrupted until 2001.