Helena Kantakouzene was the second wife of David of Trebizond, the last Emperor of Trebizond.
Helena buries her husband's corpse (Ludwig Storch, 1855)
Irene Kantakouzene
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Irene Kantakouzene, known simply as Despotess Jerina was the wife of Serbian Despot Đurađ Branković. Her father was probably the Byzantine nobleman Theodore Kantakouzenos. In Serbian folk legends, she
Helena Kantakouzene, Empress of Trebizond
…Kantakouzenos, assigned it to the unnamed wife. This was something that the historian had done elsewhere in his works, when he mistakenly also referred to Irene of Serbia, another daughter of Theodore, as Helena. Ganchou then concludes that since there is no known death date for Maria of Gothia, it may have been her who…
Irene Kantakouzene, Esphigmenou charter