Helensburgh Upper railway station serves the town of Helensburgh, Scotland, on the north shore of the Firth of Clyde to the west of Glasgow. It is located in a residential area uphill from the town centre and is by far the smaller of the town's two stations. It is on the West Highland Line, 2 miles 8 chains (3.4 km) from Craigendoran Junction, near Helensburgh, the first station on the line before Garelochhead. ScotRail manage the station and operate most services, with others provided by Caledonian Sleeper.

The West Highland Line is a railway line linking the ports of Mallaig and Oban in the Scottish Highlands to Glasgow in Central Scotland. The line was voted the top rail journey in the world by readers of independent travel magazine Wanderlust in 2009, ahead of the notable Trans-Siberian line in Russia and the Cuzco to Machu Picchu line in Peru. The ScotRail website has since reported that the line has been voted the most scenic railway line in the world for the second year running.