Henderson is a city in and the county seat of Chester County, Tennessee, United States. The population was 6,309 at the 2010 census, up from 5,670 at the 2000 census.

Chester County is a county located in the U.S. state of Tennessee. As of the 2020 census, the population was 17,341. Its county seat is Henderson. The county was created in 1879 and organized in 1882. Chester County is included in the Jackson, TN Metropolitan Statistical Area.