Henderson Street is a street in Leith, a district of the city of Edinburgh, Scotland. It forms a curving artery between Great Junction Street and an area known as the Shore, where the Water of Leith runs into the Port of Leith/Leith Docks. Henderson Street lies within the boundaries of the Leith Conservation Area and includes several listed buildings.

Leith is a port area in the north of Edinburgh, Scotland, founded at the mouth of the Water of Leith.