Henry County is a county located on the northwestern border of the U.S. state of Tennessee, and is considered part of West Tennessee. As of the 2020 census, the population was 32,199. Its county seat is Paris. The county is named for the Virginia orator and American Founding Father Patrick Henry.

West Tennessee is one of the three Grand Divisions of Tennessee that roughly comprises the western quarter of the state. The region includes 21 counties between the Tennessee and Mississippi rivers, delineated by state law. Its geography consists primarily of flat lands with rich soil and vast floodplain areas of the Mississippi River. Of the three regions, West Tennessee is the most sharply defined geographically, and is the lowest-lying. It is both the least populous and smallest, in land area, of the three Grand Divisions. Its largest city is Memphis, the state's second most populous city.