Heppner is a city in, and the county seat of, Morrow County, Oregon, United States. As of 2010, the population was 1,291. Heppner is part of the Pendleton-Hermiston Micropolitan Area. Heppner is named after Henry Heppner, a prominent Jewish-American businessman.

The Hermiston-Pendleton Micropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of two counties in Oregon anchored by the cities of Hermiston and Pendleton. Although the two communities are generally linked, the Hermiston area has been growing much faster, and is now nearly double the size of the Pendleton area. Portland State University projects that 80% of all growth in the MSA will occur in the immediate Hermiston vicinity between 2016 and 2035.