Hertford is a town and the county seat of Perquimans County, North Carolina, United States. The current population of Hertford, North Carolina is 1,912 based on the 2020 census. The US Census estimates the 2021 population at 1,925. The last official US Census in 2010 recorded the population at 2,143. Hertford is located in North Carolina's Inner Banks region and is part of both the Elizabeth City Micropolitan Statistical Area and the Hampton Roads region. It is named after the county town of Hertford, England.

Perquimans County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 13,005. Its county seat is Hertford. The Harvey Point Defense Testing Activity facility is located in Perquimans County.