Heytesbury is a village and a civil parish in Wiltshire, England. The village lies on the north bank of the Wylye, about 3+1⁄2 miles (5.6 km) southeast of the town of Warminster.

The River Wylye is a chalk stream in the south of England, with clear water flowing over gravel. It is popular with anglers for fly fishing. A half-mile stretch of the river and three lakes in Warminster are a local nature reserve.